All episodes

ATTAIN-1: Investigating Orforglipron for Obesity Management

ATTAIN-1: Investigating Orforglipron for Obesity Management

12m 22s

In this episode, Dr. Sean Wharton (University of Toronto and Wharton Medical Clinic, Canada) and Dr. Nasreen Alfaris (King Fahad Medical City, Riyadh, Saudi Arabia) join host Vivienne Parry to discuss the groundbreaking ATTAIN trial, presented at the EASD 2025 Annual Meeting in Vienna.

The trial tested Orforglipron, the first oral small molecule GLP-1 receptor agonist, showing promising results in weight reduction and cardiometabolic improvements among people living with overweight or obesity.

Beyond the data, the discussion explores what makes Orforglipron different, from its potential to expand access and affordability, to its implications for type 2 diabetes prevention. With obesity...

Pancreas Development: A Key to Discover Unexpected Treatments of Diabetes

Pancreas Development: A Key to Discover Unexpected Treatments of Diabetes

5m 23s

What does the future hold for beta cell biology and diabetes treatment? Join Prof. Raphaël Scharfmann (INSERM), recipient of the 2025 Albert Renold Prize, as he explores how developmental biology is unlocking new ways to generate functional beta cells - an important step toward curing diabetes.
In this inspiring interview from the EASD 2025 Annual Meeting in Vienna, Prof. Scharfmann discusses the progress in stem cell-derived beta cell generation, the collaboration driving translational research, and the next big challenge, counting beta cells in the living human pancreas.
Discover how decades of research are shaping the next frontier in diabetes science...

EASD-EFSD Rising Stars: The Future of Diabetes Research

EASD-EFSD Rising Stars: The Future of Diabetes Research

14m 5s

In this episode, Vivienne Parry introduces the EASD Rising Stars of 2025, four early-career researchers whose work spans exercise physiology, precision diabetes medicine, childhood obesity, and metabolic biology.

Dr Sindre Lee-Ødegård (Norway) explores exercise as medicine for highrisk groups; Dr Martin Schön (Slovakia/Germany) works on precision diabetes diagnosis and lifestyle interventions; Dr Cadenas-Sánchez (Spain) investigates childhood obesity and brain health; and Dr Jens Lund (Denmark) uncovers how metabolites like lactate act as powerful signalling molecules.

From exercise as medicine to precision diabetes care, childhood obesity, and molecular metabolism, these young scientists are redefining how we understand, prevent, and treat diabetes.Together,...

Impacting Lives of People with Diabetes in Resource Constrained Settings

Impacting Lives of People with Diabetes in Resource Constrained Settings

14m 41s

In this episode, Dr. Viswanathan Mohan, recipient of the inaugural EASD Global Impact Prize, reflects on his remarkable 50-year career transforming diabetes care in India and worldwide. From pioneering diabetes as a medical speciality and training over 29,000 educators, to leading translational research and nationwide screening initiatives, Dr. Mohan’s work has set new benchmarks in global health impact.

He discusses the evolving causes of India’s diabetes epidemic, from genetics and high-carbohydrate diets to pollution and urbanisation, and the policies needed to address them. Dr. Mohan also explores how innovation, affordability, and access to technologies like continuous glucose monitoring (CGM) can...

Everything you want to know about Adipose Tissue: From Cellular Mechanisms to Clinical Complications

Everything you want to know about Adipose Tissue: From Cellular Mechanisms to Clinical Complications

12m 16s

In this episode, EASD TV host Vivienne Parry sits with Prof. Mikael Rydén (Karolinska Institute), recipient of the 40th Camillo Golgi Prize, about his groundbreaking research on adipose tissue.

Prof. Rydén shares insights into how different fat cell subtypes influence disease progression, particularly in diabetes and obesity. His work highlights the potential of precision medicine in tailoring treatments based on the composition of adipose tissue, shifting the focus from generalised treatments to more personalised approaches.

Join us for a deep dive into how Prof. Rydén’s research is revolutionising diabetes care and what it means for the future of metabolic health.

Back to the future: Re-centring the Role of the Pancreas in Type 2 Diabetes

Back to the future: Re-centring the Role of the Pancreas in Type 2 Diabetes

8m 28s

In this episode, Dr Teresa Mezza, recipient of the 2025 EASD Minkowski Prize, takes listeners inside her pioneering research on the early mechanisms of type 2 diabetes. As both a clinician and researcher at the Fondazione Policlinico Universitario A. Gemelli in Rome, Dr Mezza studies patients before and after partial pancreatectomy, offering a unique perspective on beta cell adaptation, function, and decline.

Her work is revealing early biomarkers that could identify individuals at risk of diabetes - even before hyperglycaemia develops - paving the way for earlier intervention and prevention. Dr Mezza also discusses the importance of translational research, the...

Precision Diabetes: Learning From the Rare and Applying to the Common

Precision Diabetes: Learning From the Rare and Applying to the Common

9m 41s

In this episode, EASD host, Vivienne Parry sits down with 2025 EASD Claude Bernard Prize recipient, Prof. Andrew Hattersley, to reflect on his career which has transformed diabetes research and care worldwide. From the discovery of key genetic mutations in maturity onset diabetes of the young (MODY) and neonatal diabetes to establishing a global genetic testing programme that has helped patients in more than 100 countries, Prof. Hattersley has shaped our understanding of diabetes.

Tune in to hear reflections on his early breakthroughs, the team collaborations that made them possible, and the far-reaching clinical impact of precision medicine for children...

Mitochondria, Insulin Resistance, and the Future of Diabetes Treatment

Mitochondria, Insulin Resistance, and the Future of Diabetes Treatment

8m 25s

In this episode, we meet Prof Gerald Shulman, recipient of this year’s EASD-Novo Nordisk Foundation Diabetes Prize for Excellence, whose pioneering research has reshaped our understanding of insulin resistance and its role in type 2 diabetes and beyond.

Prof. Shulman shares insights from over four decades of research into how ectopic lipid accumulation disrupts insulin signalling, leading to diabetes, fatty liver disease, cardiovascular complications, cancers, and Alzheimer’s disease. He explains how his discoveries - from the role of diacylglycerols to innovative mitochondrial-targeted therapies now in clinical trials - could mark a paradigm shift in the treatment of insulin resistance.

Join...

The Future of Diabetes Technology: Beyond Devices to Equity and Personalisation

The Future of Diabetes Technology: Beyond Devices to Equity and Personalisation

11m 54s

In this special episode, host Vivienne Parry is joined by experts Anna Krook (Karolinska Institute), Klemen Dovč (Ljubljana University Medical Centre), Peter Gillard (University Hospital Leuven), and Julia Mader (University of Graz) to explore the rapid evolution of diabetes technology.

From continuous glucose monitors (CGMs) and automated insulin delivery (AID) systems to AI-powered apps and integrated health records, the panel discusses how these innovations are transforming care and what barriers remain.

They unpack emerging trends in personalisation, device standardisation, and the urgent need for equitable access to ensure no one is left behind. The conversation draws on insights from Diabetologia’s...

Can Pre-Diabetes Remission Reduce Global Diabetes Incidences?

Can Pre-Diabetes Remission Reduce Global Diabetes Incidences?

11m 29s

In this episode, Dr Andreas Birkenfeld (Germany) and Dr Viswanathan Mohan, 1st EASD Diabetes Global Impact Prize winner (India), join host Vivienne Parry to explore the growing importance of recognising, screening and managing pre-diabetes on a global scale.

They discuss how moving beyond diabetes remission to pre-diabetes remission could prevent long-term complications, and why strategic, risk-based screening could ease the economic burden on health systems. From policy change and health economics to public awareness and culturally tailored approaches, this episode highlights why proactive intervention in pre-diabetes is critical and what it will take to make it happen worldwide.