Diabetes Insights - Breakthroughs and Innovators

In this episode, EASD TV host Vivienne Parry sits with Prof. Mikael Rydén (Karolinska Institute), recipient of the 40th Camillo Golgi Prize, about his groundbreaking research on adipose tissue.

Prof. Rydén shares insights into how different fat cell subtypes influence disease progression, particularly in diabetes and obesity. His work highlights the potential of precision medicine in tailoring treatments based on the composition of adipose tissue, shifting the focus from generalised treatments to more personalised approaches.

Join us for a deep dive into how Prof. Rydén’s research is revolutionising diabetes care and what it means for the future of metabolic health.

In this episode, Dr Teresa Mezza, recipient of the 2025 EASD Minkowski Prize, takes listeners inside her pioneering research on the early mechanisms of type 2 diabetes. As both a clinician and researcher at the Fondazione Policlinico Universitario A. Gemelli in Rome, Dr Mezza studies patients before and after partial pancreatectomy, offering a unique perspective on beta cell adaptation, function, and decline.

Her work is revealing early biomarkers that could identify individuals at risk of diabetes - even before hyperglycaemia develops - paving the way for earlier intervention and prevention. Dr Mezza also discusses the importance of translational research, the...

In this episode, EASD host, Vivienne Parry sits down with 2025 EASD Claude Bernard Prize recipient, Prof. Andrew Hattersley, to reflect on his career which has transformed diabetes research and care worldwide. From the discovery of key genetic mutations in maturity onset diabetes of the young (MODY) and neonatal diabetes to establishing a global genetic testing programme that has helped patients in more than 100 countries, Prof. Hattersley has shaped our understanding of diabetes.

Tune in to hear reflections on his early breakthroughs, the team collaborations that made them possible, and the far-reaching clinical impact of precision medicine for children...

In this episode, we meet Prof Gerald Shulman, recipient of this year’s EASD-Novo Nordisk Foundation Diabetes Prize for Excellence, whose pioneering research has reshaped our understanding of insulin resistance and its role in type 2 diabetes and beyond.

Prof. Shulman shares insights from over four decades of research into how ectopic lipid accumulation disrupts insulin signalling, leading to diabetes, fatty liver disease, cardiovascular complications, cancers, and Alzheimer’s disease. He explains how his discoveries - from the role of diacylglycerols to innovative mitochondrial-targeted therapies now in clinical trials - could mark a paradigm shift in the treatment of insulin resistance.

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